| Resumo: | In sumary, it may well be conculuded that the nude mouse with thymus cell grafting as a severe lepromatous leprosy model was developed in C57BL/6-nu/nu as well as CF#1-nu/nu, comparing with untreated nude mice. In addtion, comparison of sex in treated group, susceptibility to M. leprae in the some males were higher than in foot swelling of the females, also, difference of individuality occured in both sex at a latter stage after infection, therefore, further investigation is under way to look for preferable nude mouse and hairless-athymic mouse which they are established by ourselves.
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